Transcription Factor ZNF281: A Novel Player in Intestinal Inflammation and Fibrosis

Transcription Factor ZNF281: A Novel Player in Intestinal Inflammation and Fibrosis

Background and aims: Recent evidences reveal the occurrence of a close relationship among epithelial to mesenchymal transition (EMT), chronic inflammation and fibrosis. ZNF281 is an EMT-inducing transcription factor (EMT-TF) involved in the regulation of pluripotency, stemness, and cancer. The aim o...

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Bibliographic Details
Main Authors: Maria Pierdomenico, Franscesca Palone, Vincenzo Cesi, Roberta Vitali, Anna Barbara Mancuso, Salvatore Cucchiara, Salvatore Oliva, Marina Aloi, Laura Stronati
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
ZNF281
intestinal inflammation
fibrosis
DSS mice
inflammatory bowel disease
pediatric patients
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02907/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02907/full

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