Benefits of Dominance over Additive Models for the Estimation of Average Effects in the Presence of Dominance

Benefits of Dominance over Additive Models for the Estimation of Average Effects in the Presence of Dominance

In quantitative genetics, the average effect at a single locus can be estimated by an additive (A) model, or an additive plus dominance (AD) model. In the presence of dominance, the AD-model is expected to be more accurate, because the A-model falsely assumes that residuals are independent and ident...

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Bibliographic Details
Main Authors: Pascal Duenk, Mario P. L. Calus, Yvonne C. J. Wientjes, Piter Bijma
Format: Article
Language:English
Published: Oxford University Press 2017-10-01
Series:G3: Genes, Genomes, Genetics
Subjects:
dominance
Hardy-Weinberg equilibrium
average effect
root mean squared error
accuracy
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.300113

Internet

http://g3journal.org/lookup/doi/10.1534/g3.117.300113

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