MicroRNA-493 suppresses tumor growth, invasion and metastasis of lung cancer by regulating E2F1.

miRNAs have been proposed to be key regulators of progression and metastasis in cancer. However, an understanding of their roles and molecular mechanisms is needed to provide deeper insights for better therapeutic opportunities. In this study we investigated the role and mechanism of miR-493 in the...

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Bibliographic Details
Main Authors: Yixue Gu, Ye Cheng, Ying Song, Zhijie Zhang, Min Deng, Chengkun Wang, Guopei Zheng, Zhimin He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25105419/pdf/?tool=EBI