The malignant pleural effusion as a model to investigate intratumoral heterogeneity in lung cancer.

Malignant Pleural Effusions (MPE) may be useful as a model to study hierarchical progression of cancer and/or intratumoral heterogeneity. To strengthen the rationale for developing the MPE-model for these purposes, we set out to find evidence for the presence of cancer stem cells (CSC) in MPE and de...

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Bibliographic Details
Main Authors: Saroj K Basak, Mysore S Veena, Scott Oh, Ge Huang, Eri Srivatsan, Min Huang, Sherven Sharma, Raj K Batra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2697051?pdf=render