Protein kinase C α enhances migration of breast cancer cells through FOXC2-mediated repression of p120-catenin

Protein kinase C α enhances migration of breast cancer cells through FOXC2-mediated repression of p120-catenin

Abstract Background Despite recent advances in the diagnosis and treatment of breast cancer, metastasis remains the main cause of death. Since migration of tumor cells is considered a prerequisite for tumor cell invasion and metastasis, a pressing goal in tumor biology has been to elucidate factors...

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Bibliographic Details
Main Authors: Thao N. D. Pham, Bethany E. Perez White, Huiping Zhao, Fariborz Mortazavi, Debra A. Tonetti
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Cancer
Subjects:
Breast cancer metastasis
Protein kinase C
p120-catenin
FOXC2
Adherens junctions
Online Access:http://link.springer.com/article/10.1186/s12885-017-3827-y

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http://link.springer.com/article/10.1186/s12885-017-3827-y

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