Differential action of glucocorticoids on apolipoprotein E gene expression in macrophages and hepatocytes.

Apolipoprotein E (apoE) has anti-atherosclerotic properties, being involved in the transport and clearance of cholesterol-rich lipoproteins as well as in cholesterol efflux from cells. We hypothesized that glucocorticoids may exert anti-inflammatory properties by increasing the level of macrophage-d...

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Bibliographic Details
Main Authors: Violeta Georgeta Trusca, Elena Valeria Fuior, Ioana Madalina Fenyo, Dimitris Kardassis, Maya Simionescu, Anca Violeta Gafencu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5371326?pdf=render