A BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses

A BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses

Lysine63-linked ubiquitin (K63-Ub) chains represent a particular ubiquitin topology that mediates proteasome-independent signaling events. The deubiquitinating enzyme (DUB) BRCC36 segregates into distinct nuclear and cytoplasmic complexes that are specific for K63-Ub hydrolysis. RAP80 targets the f...

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Bibliographic Details
Main Authors: Hui Zheng, Vibhor Gupta, Jeffrey Patterson-Fortin, Sabyasachi Bhattacharya, Kanstantsin Katlinski, Junmin Wu, Bentley Varghese, Christopher J. Carbone, Bernadette Aressy, Serge Y. Fuchs, Roger A. Greenberg
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471300466X

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http://www.sciencedirect.com/science/article/pii/S221112471300466X

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