Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1

Abstract Background Androgen deprivation therapy (ADT) is the main clinical treatment for patients with advanced prostate cancer (PCa). However, PCa eventually progresses to castration‐resistant prostate cancer (CRPC), largely because of androgen receptor variation and increased intratumoral androge...

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Bibliographic Details
Main Authors: Lijie Zhou, Cai Zhang, Xiong Yang, Lilong Liu, Junyi Hu, Yaxin Hou, Hong Tao, Haruhiko Sugimura, Zhaohui Chen, Liang Wang, Ke Chen
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.449