Involvement of the Long-Chain Fatty Acid Receptor GPR40 in Depression-Related Behavior

Abstract.: The functional role of brain G protein–coupled receptor 40 (GPR40) remains unclear. We investigated GPR40 signaling in depression-related behavior in mice via the forced swim test. A repeated but not a single intracerebroventricular administration of the GPR40 agonist, GW9508, reduced the...

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Bibliographic Details
Main Authors: Takashi Nishinaka, Takuya Yamashita, Kazuo Nakamoto, Fumiyo Kasuya, Shogo Tokuyama
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319301598