Networked T cell death following macrophage infection by Mycobacterium tuberculosis.
BACKGROUND: Depletion of T cells following infection by Mycobacterium tuberculosis (Mtb) impairs disease resolution, and interferes with clinical test performance that relies on cell-mediated immunity. A number of mechanisms contribute to this T cell suppression, such as activation-induced death and...
Main Authors: | Stephen H-F Macdonald, Elliott Woodward, Michelle M Coleman, Emma R Dorris, Parthiban Nadarajan, Wui-Mei Chew, Anne-Marie McLaughlin, Joseph Keane |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3366923?pdf=render |
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