Chemoresistance and the Self-Maintaining Tumor Microenvironment

The progression of cancer is associated with alterations in the tumor microenvironment, including changes in extracellular matrix (ECM) composition, matrix rigidity, hypervascularization, hypoxia, and paracrine factors. One key malignant phenotype of cancer cells is their ability to resist chemother...

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Bibliographic Details
Main Authors: Gulcen Yeldag, Alistair Rice, Armando del Río Hernández
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cancers
Subjects:
ECM
Online Access:https://www.mdpi.com/2072-6694/10/12/471