Comparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson's Disease.

Comparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson's Disease.

Cerebral dopamine neurotrophic factor (CDNF) belongs to a newly discovered family of evolutionarily conserved neurotrophic factors. We demonstrate for the first time a therapeutic effect of CDNF in a unilateral 6-hydroxydopamine (6-OHDA) lesion model of Parkinson's disease in marmoset monkeys....

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Bibliographic Details
Main Authors: Enrique Garea-Rodríguez, Ave Eesmaa, Päivi Lindholm, Christina Schlumbohm, Jessica König, Birgit Meller, Kerstin Krieglstein, Gunther Helms, Mart Saarma, Eberhard Fuchs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4763937?pdf=render

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http://europepmc.org/articles/PMC4763937?pdf=render

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