G Protein-Coupled Receptors: What a Difference a ‘Partner’ Makes

G protein-coupled receptors (GPCRs) are important cell signaling mediators, involved in essential physiological processes. GPCRs respond to a wide variety of ligands from light to large macromolecules, including hormones and small peptides. Unfortunately, mutations and dysregulation of GPCRs that in...

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Bibliographic Details
Main Authors: Benoît T. Roux, Graeme S. Cottrell
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/15/1/1112