Antioxidant and Protective Mechanisms against Hypoxia and Hypoglycaemia in Cortical Neurons in Vitro

Antioxidant and Protective Mechanisms against Hypoxia and Hypoglycaemia in Cortical Neurons in Vitro

In the present work, we have studied whether cell death could be induced in cortical neurons from rats subjected to different period of O2 deprivation and low glucose (ODLG). This “in vitro” model is designed to emulate the penumbra area under ischemia. In these conditions, cortical neurons displaye...

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Bibliographic Details
Main Authors: José Joaquín Merino, César Roncero, María Jesús Oset-Gasque, Ahmad Naddaf, María Pilar González
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:International Journal of Molecular Sciences
Subjects:
cortical neurons
cerebral ischemia
ROS formation
antioxidant defenses
mitochondrial membrane potential
free radical
SOD1/caspase-3
Online Access:http://www.mdpi.com/1422-0067/15/2/2475

Internet

http://www.mdpi.com/1422-0067/15/2/2475

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