The application of the Escherichia coli giant spheroplast for drug screening with automated planar patch clamp system

Kv2.1, the voltage-gated ion channel, is ubiquitously expressed in variety of tissues and dysfunction of this ion channel is responsible for multiple diseases. Electrophysiological properties of ion channels are so far characterized with eukaryotic cells using the manual patch clamp which requires s...

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Bibliographic Details
Main Authors: Kyoko Kikuchi, Mika Sugiura, Chizuko Nishizawa-Harada, Tadashi Kimura
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Biotechnology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X15000260