Brain tissue oxidative damage as a possible mechanism for the deleterious effect of a chronic high dose of estradiol on learning and memory in ovariectomized rats

In addition to antioxidative effects, estrogens also exert pro-oxidative actions. The effect of chronic administration of a high dose of estradiol valerate on Morris water maze tasks and brain tissues oxidative damage was investigated. The Sham-Est and OVX-Est groups were treated with estradiol vale...

Full description

Bibliographic Details
Main Authors: Fatimeh Khodabandehloo, Mahmoud Hosseini, Ziba Rajaei, Mohammad Soukhtanloo, Esmaeil Farrokhi, Mohsen Rezaeipour
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2013-05-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000500313&lng=en&tlng=en