Quantitative Assessment of Tissue Biomarkers and Construction of a Model to Predict Outcome in Breast Cancer Using Multiple Imputation

Missing data pose one of the greatest challenges in the rigorous evaluation of biomarkers. The limited availability of specimens with complete clinical annotation and quality biomaterial often leads to underpowered studies. Tissue microarray studies, for example, may be further handicapped by the lo...

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Bibliographic Details
Main Authors: John W. Emerson, Marisa Dolled-Filhart, Lyndsay Harris, David L. Rimm, David P. Tuck
Format: Article
Language:English
Published: SAGE Publishing 2009-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S911