Quantitative Assessment of Tissue Biomarkers and Construction of a Model to Predict Outcome in Breast Cancer Using Multiple Imputation
Missing data pose one of the greatest challenges in the rigorous evaluation of biomarkers. The limited availability of specimens with complete clinical annotation and quality biomaterial often leads to underpowered studies. Tissue microarray studies, for example, may be further handicapped by the lo...
Main Authors: | John W. Emerson, Marisa Dolled-Filhart, Lyndsay Harris, David L. Rimm, David P. Tuck |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2009-01-01
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Series: | Cancer Informatics |
Online Access: | https://doi.org/10.4137/CIN.S911 |
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