TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility.

TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility.

Cellular migration and contractility are fundamental processes that are regulated by a variety of concerted mechanisms such as cytoskeleton rearrangements, focal adhesion turnover, and Ca2+ oscillations. TRPM4 is a Ca2+-activated non-selective cationic channel (Ca2+-NSCC) that conducts monovalent bu...

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Bibliographic Details
Main Authors: Mónica Cáceres, Liliana Ortiz, Tatiana Recabarren, Anibal Romero, Alicia Colombo, Elías Leiva-Salcedo, Diego Varela, José Rivas, Ian Silva, Diego Morales, Camilo Campusano, Oscar Almarza, Felipe Simon, Hector Toledo, Kang-Sik Park, James S Trimmer, Oscar Cerda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4482413?pdf=render

Internet

http://europepmc.org/articles/PMC4482413?pdf=render

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