Regional lung deflation with increased airway volume underlies the functional response to bronchodilators in chronic obstructive pulmonary disease

Abstract Bronchodilators, including long‐acting muscarinic antagonists (LAMAs), improve airflow limitation and lung hyperinflation in patients with chronic obstructive pulmonary disease (COPD). While bronchodilators increase airway caliber and deflate the lungs, little is known about the effects of...

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Bibliographic Details
Main Authors: Naoya Tanabe, Susumu Sato, Shigeo Muro, Hiroshi Shima, Tsuyoshi Oguma, Kazuya Tanimura, Atsuyasu Sato, Toyohiro Hirai
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Physiological Reports
Subjects:
CT
Online Access:https://doi.org/10.14814/phy2.14330