Differential regulation of polarized synaptic vesicle trafficking and synapse stability in neural circuit rewiring in Caenorhabditis elegans.

Neural circuits are dynamic, with activity-dependent changes in synapse density and connectivity peaking during different phases of animal development. In C. elegans, young larvae form mature motor circuits through a dramatic switch in GABAergic neuron connectivity, by concomitant elimination of exi...

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Bibliographic Details
Main Authors: Naina Kurup, Dong Yan, Karina Kono, Yishi Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5500376?pdf=render