Differential Contribution of the Guanylyl Cyclase-Cyclic GMP-Protein Kinase G Pathway to the Proliferation of Neural Stem Cells Stimulated by Nitric Oxide

Differential Contribution of the Guanylyl Cyclase-Cyclic GMP-Protein Kinase G Pathway to the Proliferation of Neural Stem Cells Stimulated by Nitric Oxide

Nitric oxide (NO) is an important inflammatory mediator involved in the initial boost in the proliferation of neural stem cells following brain injury. However, the mechanisms underlying the proliferative effect of NO are still unclear. The aim of this work was to investigate whether cyclic GMP (cGM...

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Bibliographic Details
Main Authors: Bruno P. Carreira, Maria Inês Morte, Ana Sofia Lourenço, Ana Isabel Santos, Ângela Inácio, António F. Ambrósio, Caetana M. Carvalho, Inês M. Araújo
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2012-02-01
Series:Neurosignals
Subjects:
Nitric oxide
Neural stem cells
cyclic GMP
cGMP-dependent kinase
Proliferation
Neurogenesis
Guanylyl cyclase
Online Access:http://www.karger.com/Article/FullText/332811

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http://www.karger.com/Article/FullText/332811

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