Effects of ergotamine on the central nervous system using untargeted metabolomics analysis in a mouse model

Abstract The ergot alkaloid ergotamine is produced by Claviceps purpurea, a parasitic fungus that commonly infects crops and pastures of high agricultural and economic importance. In humans and livestock, symptoms of ergotism include necrosis and gangrene, high blood pressure, heart rate, thermoregu...

Full description

Bibliographic Details
Main Authors: Priyanka Reddy, Delphine Vincent, Joanne Hemsworth, Vilnis Ezernieks, Kathryn Guthridge, German C. Spangenberg, Simone J. Rochfort
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98870-4