Hypoxia Preconditioning of Human MSCs: a Direct Evidence of HIF-1α and Collagen Type XV Correlation

Background/Aims: Mesenchymal stromal cells (MSCs) hold considerable promise in bone tissue engineering, but their poor survival and potency when in vivo implanted limits their therapeutic potential. For this reason, the study on culture conditions and cellular signals that can influence the potentia...

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Main Authors: Elisabetta Lambertini, Letizia Penolazzi, Marco Angelozzi, Leticia Scussel Bergamin, Cristina Manferdini, Francesco Vieceli Dalla Sega, Francesca Paolella, Gina Lisignoli, Roberta Piva
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:https://www.karger.com/Article/FullText/495869