Monasone Naphthoquinone Biosynthesis and Resistance in Monascus Fungi

Monasone Naphthoquinone Biosynthesis and Resistance in Monascus Fungi

The genes for Monascus naphthoquinone (monasone) biosynthesis are embedded in and form a composite supercluster with the Monascus azaphilone pigment biosynthetic gene cluster. Early biosynthetic intermediates are shared by the two pathways. Some enzymes encoded by the supercluster play double duty i...

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Bibliographic Details
Main Authors: Mu Li, Lijing Kang, Xiaoli Ding, Jiao Liu, Qingpei Liu, Yanchun Shao, István Molnár, Fusheng Chen
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mBio
Subjects:
monascus spp.
naphthoquinone
nested biosynthetic pathway
supercluster
resistance mechanism
Online Access:https://doi.org/10.1128/mBio.02676-19

Internet

https://doi.org/10.1128/mBio.02676-19

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