Extra-Chromosomal DNA Sequencing Reveals Episomal Prophages Capable of Impacting Virulence Factor Expression in Staphylococcus aureus

Extra-Chromosomal DNA Sequencing Reveals Episomal Prophages Capable of Impacting Virulence Factor Expression in Staphylococcus aureus

Staphylococcus aureus is a major human pathogen with well-characterized bacteriophage contributions to its virulence potential. Recently, we identified plasmidial and episomal prophages in S. aureus strains using an extra-chromosomal DNA (exDNA) isolation and sequencing approach, uncovering the plas...

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Bibliographic Details
Main Authors: Douglas R. Deutsch, Bryan Utter, Kathleen J. Verratti, Heike Sichtig, Luke J. Tallon, Vincent A. Fischetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
bacteriophages
extra-chromosomal DNA
episomal
plasmidial
active lysogeny
virulence factor
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01406/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01406/full

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