The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice

The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice

Aim: NADPH oxidases are important sources of reactive oxygen species (ROS). Several Nox homologues are present together in the vascular system but whether they exhibit crosstalk at the activity level is unknown. To address this, vessel function of knockout mice for the cytosolic Nox organizer protei...

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Bibliographic Details
Main Authors: Flávia Rezende, Franziska Moll, Maria Walter, Valeska Helfinger, Fabian Hahner, Patrick Janetzko, Christian Ringel, Andreas Weigert, Ingrid Fleming, Norbert Weissmann, Carsten Kuenne, Mario Looso, Michael A. Rieger, Peter Nawroth, Thomas Fleming, Ralf P. Brandes, Katrin Schröder
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Redox Biology
Subjects:
NADPH oxidase
NoxO1
Nox1
p47phox
Superoxide
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717306195

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http://www.sciencedirect.com/science/article/pii/S2213231717306195

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