Comparative In Vitro Immune Stimulation Analysis of Primary Human B Cells and B Cell Lines

B cell specific immunomodulatory drugs still remain an unmet medical need. Utilisation of validated simplified in vitro models would allow readily obtaining new insights in the complexity of B cell regulation. For this purpose we investigated which human B lymphocyte stimulation assays may be ideall...

Full description

Bibliographic Details
Main Authors: Kristien Van Belle, Jean Herman, Louis Boon, Mark Waer, Ben Sprangers, Thierry Louat
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2016/5281823