An experimental-mathematical approach to predict tumor cell growth as a function of glucose availability in breast cancer cell lines.

We present the development and validation of a mathematical model that predicts how glucose dynamics influence metabolism and therefore tumor cell growth. Glucose, the starting material for glycolysis, has a fundamental influence on tumor cell growth. We employed time-resolved microscopy to track th...

Full description

Bibliographic Details
Main Authors: Jianchen Yang, Jack Virostko, David A Hormuth, Junyan Liu, Amy Brock, Jeanne Kowalski, Thomas E Yankeelov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0240765