Genetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.

Genetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.

Weight-loss interventions generally improve lipid profiles and reduce cardiovascular disease risk, but effects are variable and may depend on genetic factors. We performed a genetic association analysis of data from 2,993 participants in the Diabetes Prevention Program to test the hypotheses that a...

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Bibliographic Details
Main Authors: Toni I Pollin, Tamara Isakova, Kathleen A Jablonski, Paul I W de Bakker, Andrew Taylor, Jarred McAteer, Qing Pan, Edward S Horton, Linda M Delahanty, David Altshuler, Alan R Shuldiner, Ronald B Goldberg, Jose C Florez, Paul W Franks, Diabetes Prevention Program Research Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3431328?pdf=render

Internet

http://europepmc.org/articles/PMC3431328?pdf=render

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