Prediction of Long-Term Benefits of Inhaled Steroids by Phenotypic Markers in Moderate-to-Severe COPD: A Randomized Controlled Trial.

BACKGROUND:The decline in lung function can be reduced by long-term inhaled corticosteroid (ICS) treatment in subsets of patients with chronic obstructive pulmonary disease (COPD). We aimed to identify which clinical, physiological and non-invasive inflammatory characteristics predict the benefits o...

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Main Authors: Jiska B Snoeck-Stroband, Therese S Lapperre, Peter J Sterk, Pieter S Hiemstra, Henk A Thiadens, H Marike Boezen, Nick H T Ten Hacken, Huib A M Kerstjens, Dirkje S Postma, Wim Timens, Jacob K Sont, GLUCOLD Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4699453?pdf=render