Genotype of Null Polymorphisms in Genes GSTM1, GSTT1, CYP1A1, and CYP1A1*2A (rs4646903 T>C)/CYP1A1*2C (rs1048943 A>G) in Patients with Larynx Cancer in Southeast Spain

Genotype of Null Polymorphisms in Genes GSTM1, GSTT1, CYP1A1, and CYP1A1*2A (rs4646903 T>C)/CYP1A1*2C (rs1048943 A>G) in Patients with Larynx Cancer in Southeast Spain

Background: some types of cancer have been associated with the presence of single nucleotide polymorphisms (SNPs) of some genes that encode enzymes: glutathione-S transferase (GST), whose alteration leads to loss of function and a lower capacity to eliminate toxic GSTM1 and GSTT1 null genotypes; SNP...

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Bibliographic Details
Main Authors: Mariano Sánchez-Siles, Juan Pablo Pelegrín-Hernández, Diego Hellin-Meseguer, Yolanda Guerrero-Sánchez, Andrés Corno-Caparrós, Juan Cabezas-Herrera, Francisco Pastor-Quirante, José Alberto Fernández-Ruiz, Alfonso Aliaga-Sánchez, Mayra Lucero-Berdugo, Fabio Camacho-Alonso
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
larynx cancer
single nucleotide polymorphisms
GSTM1
GSTT1
CYP1A1
CYP1A1–2
Online Access:https://www.mdpi.com/2072-6694/12/9/2478

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https://www.mdpi.com/2072-6694/12/9/2478

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