Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology

Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology

Alzheimer's disease (AD) is characterized by loss of specific cell populations within selective subregions of the hippocampus. Excitotoxicity, mediated via ionotropic glutamate receptors, may play a crucial role in this selective neuronal vulnerability. We investigated whether alterations in NM...

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Bibliographic Details
Main Authors: Amanda J Mishizen-Eberz, Robert A Rissman, Troy L Carter, Milos D Ikonomovic, Barry B Wolfe, David M Armstrong
Format: Article
Language:English
Published: Elsevier 2004-02-01
Series:Neurobiology of Disease
Subjects:
NMDA receptor
Alzheimer's disease
Hippocampus
In situ hybridization
Western blot
Neuropathology
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103001918

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http://www.sciencedirect.com/science/article/pii/S0969996103001918

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