Rapamycin Protects Against High Fat Diet–Induced Obesity in C57BL/6J Mice

Rapamycin (RAPA), an immunosuprpressive drug used extensively to prevent graft rejection in transplant patients, has been reported to inhibit adipogenesis in vitro. In this study, we investigated the anti-obesity effects of RAPA in C57BL/6J mice on a high-fat diet (HFD). Mice treated with RAPA (2 mg...

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Bibliographic Details
Main Authors: Geng-Ruei Chang, Yi-Shin Chiu, Ying-Ying Wu, Wen-Ying Chen, Jiunn-Wang Liao, Te-Hsin Chao, Frank Chiahung Mao
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319312307