Depletion of the actin bundling protein SM22/transgelin increases actin dynamics and enhances the tumourigenic phenotypes of cells

<p>Abstract</p> <p>Background</p> <p>SM22 has long been studied as an actin-associated protein. Interestingly, levels of SM22 are often reduced in tumour cell lines, while they are increased during senescence possibly indicating a role for SM22 in cell fate decisions vi...

Full description

Bibliographic Details
Main Authors: Thompson Oliver, Moghraby Jeelan S, Ayscough Kathryn R, Winder Steve J
Format: Article
Language:English
Published: BMC 2012-01-01
Series:BMC Cell Biology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2121/13/1