Worldwide genetic variability of the Duffy binding protein: insights into Plasmodium vivax vaccine development.

The dependence of Plasmodium vivax on invasion mediated by Duffy binding protein (DBP) makes this protein a prime candidate for development of a vaccine. However, the development of a DBP-based vaccine might be hampered by the high variability of the protein ligand (DBP(II)), known to bias the immun...

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Bibliographic Details
Main Authors: Taís Nóbrega de Sousa, Luzia Helena Carvalho, Cristiana Ferreira Alves de Brito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3149059?pdf=render