Direct Lymph Node Vaccination of Lentivector/Prostate-Specific Antigen is Safe and Generates Tissue-Specific Responses in Rhesus Macaques

Direct Lymph Node Vaccination of Lentivector/Prostate-Specific Antigen is Safe and Generates Tissue-Specific Responses in Rhesus Macaques

Anti-cancer immunotherapy is emerging from a nadir and demonstrating tangible benefits to patients. A variety of approaches are now employed. We are invoking antigen (Ag)-specific responses through direct injections of recombinant lentivectors (LVs) that encode sequences for tumor-associated antigen...

Full description

Bibliographic Details
Main Authors: Bryan C. Au, Chyan-Jang Lee, Orlay Lopez-Perez, Warren Foltz, Tania C. Felizardo, James C.M. Wang, Ju Huang, Xin Fan, Melissa Madden, Alyssa Goldstein, David A. Jaffray, Badru Moloo, J. Andrea McCart, Jeffrey A. Medin
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Biomedicines
Subjects:
preclinical
lentivector
immunotherapy
cancer vaccine
prostate cancer
Online Access:http://www.mdpi.com/2227-9059/4/1/6

Internet

http://www.mdpi.com/2227-9059/4/1/6

Similar Items