p53 mutation regulates PKD genes and results in co-occurrence of PKD and tumorigenesis

p53 mutation regulates PKD genes and results in co-occurrence of PKD and tumorigenesis

<b>Objective</b> Polycystic kidney disease (PKD) is the major cause of kidney failure and mortality in humans. It has always been suspected that the development of cystic kidney disease shares features with tumorigenesis, although the evidence is unclear. <b>Methods</b&g...

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Bibliographic Details
Main Authors: Haili Li, Yongjin Zhang, Juhua Dan, Ruoyu Zhou, Cui Li, Rong Li, Xiaoming Wu, Sanjay Kumar Singh, Jeffrey T. Chang, Julun Yang, Ying Luo
Format: Article
Language:English
Published: China Anti-Cancer Association 2019-03-01
Series:Cancer Biology & Medicine
Subjects:
p53 mutation
telomere dysfunction
polycystic kidney disease
tumorigenesis
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1363

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1363

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