Demyelination in mild cognitive impairment suggests progression path to Alzheimer's disease.

The preclinical Alzheimer's disease (AD) - amnestic mild cognitive impairment (MCI) - is manifested by phenotypes classified into exclusively memory (single-domain) MCI (sMCI) and multiple-domain MCI (mMCI). We suggest that typical MCI-to-AD progression occurs through the sMCI-to-mMCI sequence...

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Bibliographic Details
Main Authors: Cristian Carmeli, Alessia Donati, Valérie Antille, Dragana Viceic, Joseph Ghika, Armin von Gunten, Stephanie Clarke, Reto Meuli, Richard S Frackowiak, Maria G Knyazeva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3758332?pdf=render