Early loss of Scribble affects cortical development, interhemispheric connectivity and psychomotor activity

Early loss of Scribble affects cortical development, interhemispheric connectivity and psychomotor activity

Abstract Neurodevelopmental disorders arise from combined defects in processes including cell proliferation, differentiation, migration and commissure formation. The evolutionarily conserved tumor-suppressor protein Scribble (Scrib) serves as a nexus to transduce signals for the establishment of api...

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Bibliographic Details
Main Authors: Jerome Ezan, Maité M. Moreau, Tamrat M. Mamo, Miki Shimbo, Maureen Decroo, Melanie Richter, Ronan Peyroutou, Rivka Rachel, Fadel Tissir, Froylan Calderon de Anda, Nathalie Sans, Mireille Montcouquiol
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88147-1

Internet

https://doi.org/10.1038/s41598-021-88147-1

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