Attenuation of Red Blood Cell Storage Lesions with Vitamin C

Attenuation of Red Blood Cell Storage Lesions with Vitamin C

Stored red blood cells (RBCs) undergo oxidative stress that induces deleterious metabolic, structural, biochemical, and molecular changes collectively referred to as “storage lesions”. We hypothesized that vitamin C (VitC, reduced or oxidized) would reduce red cell storage lesions, thus prolonging t...

Full description

Bibliographic Details
Main Authors: Kimberly Sanford, Bernard J. Fisher, Evan Fowler, Alpha A. Fowler, Ramesh Natarajan
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Antioxidants
Subjects:
vitamin C
RBC storage lesions
mean fragility index
β-spectrin
scanning electron microscopy
Online Access:https://www.mdpi.com/2076-3921/6/3/55

Internet

https://www.mdpi.com/2076-3921/6/3/55

Similar Items