Bacterial TLR4 and NOD2 signaling linked to reduced mitochondrial energy function in active inflammatory bowel disease

Bacterial TLR4 and NOD2 signaling linked to reduced mitochondrial energy function in active inflammatory bowel disease

Inflammatory bowel disease (IBD) has been linked to active signaling with bacterial components and reduced mitochondrial ATP production; however, synergism between both of these disease characteristics remains unclear. We aimed to determine in human IBD transcriptomes the link between a transcriptio...

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Bibliographic Details
Main Authors: Emmanuelle Ruiz, Harrison M. Penrose, Sandra Heller, Hani Nakhoul, Melody Baddoo, Erik F. Flemington, Emad Kandil, Suzana D. Savkovic
Format: Article
Language:English
Published: Taylor & Francis Group 2020-05-01
Series:Gut Microbes
Subjects:
tlr4
nod2
mitochondria
inflammatory bowel disease
bioinformatics
Online Access:http://dx.doi.org/10.1080/19490976.2019.1611152

Internet

http://dx.doi.org/10.1080/19490976.2019.1611152

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