Genomic profiles and tumor immune microenvironment of primary lung carcinoma and brain oligo-metastasis

Abstract Brain metastasis (BM) is a common malignant event in lung cancer. Here, we recruited 33 lung cancer patients with brain oligo-metastasis to explore the genomic features and tumor immune microenvironment (TIME) of the lung and BM independently. For genomic profiling, targeted sequencing was...

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Bibliographic Details
Main Authors: Zhengbo Song, Ling Yang, Zhipeng Zhou, Pansong Li, Wenxian Wang, Guoping Cheng, Rongrong Chen, Lianpeng Chang, Yiping Zhang, Yanfang Guan, Xuefeng Xia, Xin Yi, Rongrong Zhou, Ming Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03410-7