Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway

Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway

Abstract: AKT, a serine/threonine protein kinase and mammalian target of rapamycin (mTOR) plays a critical role in the proliferation and resistance to apoptosis that are essential to the development and progression of colon cancer. Therefore, AKT/mTOR signaling pathway has been recognized as an attr...

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Bibliographic Details
Main Authors: Małgorzata Kapral, Joanna Wawszczyk, Katarzyna Jesse, Monika Paul-Samojedny, Dariusz Kuśmierz, Ludmiła Węglarz
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
colon cancer
InsP6
proliferation
apoptosis
AKT
mTOR
Online Access:https://www.mdpi.com/1420-3049/22/10/1657

Internet

https://www.mdpi.com/1420-3049/22/10/1657

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