Modulation of epidermal transcription circuits in psoriasis: new links between inflammation and hyperproliferation.

Whole-genome expression profiling has been used to characterize molecular-level differences between psoriasis lesions and normal skin. Pathway analysis, however, is complicated by the fact that expression profiles have been derived from bulk skin biopsies with RNA derived from multiple cell types.We...

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Bibliographic Details
Main Authors: William R Swindell, Andrew Johnston, Xianying Xing, John J Voorhees, James T Elder, Johann E Gudjonsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3829857?pdf=render