Cardiac Versus Renal Response to Volume Expansion in Preclinical Systolic Dysfunction With PDEV Inhibition and BNP

Cardiac Versus Renal Response to Volume Expansion in Preclinical Systolic Dysfunction With PDEV Inhibition and BNP

Summary: Impaired cardiorenal response to acute saline volume expansion in preclinical systolic dysfunction (PSD) may lead to symptomatic heart failure. The objective was to determine if combination phosphodiesterase-V inhibition and exogenous B-type natriuretic peptide (BNP) administration may enha...

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Bibliographic Details
Main Authors: Siu-Hin Wan, MD, Isabel Torres-Courchoud, MD, PhD, Paul M. McKie, MD, Joshua P. Slusser, BSc, Margaret M. Redfield, MD, John C. Burnett, Jr., MD, David O. Hodge, MS, Horng H. Chen, MBBCh
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X19302633

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http://www.sciencedirect.com/science/article/pii/S2452302X19302633

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