Actomyosin-driven force patterning controls endocytosis at the immune synapse

Actomyosin-driven force patterning controls endocytosis at the immune synapse

The immune synapse promotes cellular information exchange but the role of biophysical forces in synapse function is unclear. Here, the authors show that B cells exert two types of forces, a centripetal myosin II-driven force and a central actin protrusive force at the site of antigen extraction.

Bibliographic Details
Main Authors: Anita Kumari, Judith Pineau, Pablo J. Sáez, Mathieu Maurin, Danielle Lankar, Mabel San Roman, Katharina Hennig, Vanessa F. Boura, Raphael Voituriez, Mikael C. I. Karlsson, Martial Balland, Ana-Maria Lennon Dumenil, Paolo Pierobon
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10751-7

Internet

https://doi.org/10.1038/s41467-019-10751-7

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