Presence of new mutations in the TP53 gene in patients with low-risk myelodysplastic syndrome: two case reports

Presence of new mutations in the TP53 gene in patients with low-risk myelodysplastic syndrome: two case reports

Abstract Background Myelodysplastic syndromes are heterogeneous disorders. Patients with myelodysplastic syndrome disease often have ineffective hematopoiesis, cytopenias, blood cell dysplasia in one or more cell types, and are at high risk for developing acute myeloid leukemia. In myelodysplastic s...

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Bibliographic Details
Main Authors: Fernando Barroso Duarte, Romélia Pinheiro Gonçalves Lemes, Talyta Ellen de Jesus dos Santos, Maritza Cavalcante Barbosa, João Paulo Leitão de Vasconcelos, Francisco Dário Rocha-Filho, Ilana Zalcberg, Diego Coutinho, Monalisa Feliciano Figueiredo, Luciana Barros Carlos, Paulo Roberto Leitão de Vasconcelos
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Medical Case Reports
Subjects:
Myelodysplastic syndromes
TP53 mutations
Prognosis
Online Access:http://link.springer.com/article/10.1186/s13256-017-1301-8

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http://link.springer.com/article/10.1186/s13256-017-1301-8

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