Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation

Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation

Intestinal stem cells (ISCs) maintain and repair the intestinal epithelium. While regeneration after ISC-targeted damage is increasingly understood, injury-repair mechanisms that direct regeneration following injuries to differentiated cells remain uncharacterized. The enteric pathogen, rotavirus, i...

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Bibliographic Details
Main Authors: Winnie Y. Zou, Sarah E. Blutt, Xi-Lei Zeng, Min-Shan Chen, Yuan-Hung Lo, David Castillo-Azofeifa, Ophir D. Klein, Noah F. Shroyer, Mark Donowitz, Mary K. Estes
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cell Reports
Subjects:
rotavirus
RV
intestinal stem cell
ISC
epithelial WNT
regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717319307

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http://www.sciencedirect.com/science/article/pii/S2211124717319307

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