Peroxisome Proliferator-Activated Receptor Gamma Exacerbates Concanavalin A-Induced Liver Injury via Suppressing the Translocation of NF-κB into the Nucleus

Peroxisome Proliferator-Activated Receptor Gamma Exacerbates Concanavalin A-Induced Liver Injury via Suppressing the Translocation of NF-κB into the Nucleus

Peroxisome proliferator-activated receptor-γ (PPARγ) has been reported to reduce inflammation and attenuate fibrosis in the liver. In this study, we investigated the effects of PPARγ on the liver injury induced by 20 mg/kg Concanavalin A (Con A). The mice were administered one of the three types of...

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Main Authors: Yuji Ogawa, Masato Yoneda, Wataru Tomeno, Kento Imajo, Yoshiyasu Shinohara, Koji Fujita, Wataru Shibata, Hiroyuki Kirikoshi, Satoru Saito, Koichiro Wada, Shin Maeda, Atsushi Nakajima
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2012/940384

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http://dx.doi.org/10.1155/2012/940384

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